Mitotic phosphorylation stimulates DNA relaxation activity of human topoisomerase I.

Hackbarth, Jennifer S

Mitotic phosphorylation stimulates DNA relaxation activity of human topoisomerase I. [electronic resource] - The Journal of biological chemistry Jun 2008 - 16711-22 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

0021-9258

10.1074/jbc.M802246200 doi


Amino Acid Sequence
CDC2 Protein Kinase--metabolism
Camptothecin--pharmacology
DNA--chemistry
DNA Topoisomerases, Type I--chemistry
Gene Expression Regulation, Enzymologic
Humans
K562 Cells
Mitosis
Models, Biological
Molecular Sequence Data
Mutagenesis, Site-Directed
Phosphorylation
Sequence Homology, Amino Acid
Serine--chemistry