Involvement of the nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway in the antihyperalgesic effects of bovine lactoferrin in a model of neuropathic pain.

Wang, Jun

Involvement of the nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway in the antihyperalgesic effects of bovine lactoferrin in a model of neuropathic pain. [electronic resource] - Brain research May 2008 - 1-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-8993

10.1016/j.brainres.2008.03.004 doi


Analgesics--pharmacology
Animals
Cattle
Cyclic GMP--metabolism
Cyclic GMP-Dependent Protein Kinases--metabolism
Disease Models, Animal
Dose-Response Relationship, Drug
Enzyme Inhibitors--pharmacology
Hyperalgesia--drug therapy
Injections, Spinal
Lactoferrin--pharmacology
Male
Narcotic Antagonists--pharmacology
Neurons, Afferent--drug effects
Nitric Oxide--metabolism
Peripheral Nervous System Diseases--drug therapy
Potassium Channel Blockers--pharmacology
Potassium Channels--drug effects
Rats
Rats, Sprague-Dawley
Receptors, Opioid, mu--drug effects
Signal Transduction--drug effects