Persistent activation of Akt or ERK prevents the toxicity induced by saturated and polyunsaturated fatty acids in RINm5F β-cells.

Simon, Monique Nouailhetas

Persistent activation of Akt or ERK prevents the toxicity induced by saturated and polyunsaturated fatty acids in RINm5F β-cells. [electronic resource] - Toxicology in vitro : an international journal published in association with BIBRA Jun 2008 - 1018-24 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0887-2333

10.1016/j.tiv.2008.02.012 doi


Animals
Cell Death--drug effects
Cell Line, Tumor
Dose-Response Relationship, Drug
Enzyme Activation--drug effects
Extracellular Signal-Regulated MAP Kinases--drug effects
Fatty Acids--administration & dosage
Fatty Acids, Unsaturated--administration & dosage
Insulin-Secreting Cells--drug effects
Insulinoma--metabolism
Phosphorylation--drug effects
Protein Kinase C-delta--drug effects
Proto-Oncogene Proteins c-akt--drug effects
Rats
Time Factors