c-Myc represses FOXO3a-mediated transcription of the gene encoding the p27(Kip1) cyclin dependent kinase inhibitor.

Chandramohan, Vidyalakshmi

c-Myc represses FOXO3a-mediated transcription of the gene encoding the p27(Kip1) cyclin dependent kinase inhibitor. [electronic resource] - Journal of cellular biochemistry Aug 2008 - 2091-106 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1097-4644

10.1002/jcb.21765 doi


Animals
Apoptosis
Binding Sites
Cell Line
Cyclin-Dependent Kinase Inhibitor p27--genetics
Forkhead Box Protein O3
Forkhead Transcription Factors--chemistry
Gene Expression Regulation, Neoplastic
Humans
Mice
Neoplasms--enzymology
Promoter Regions, Genetic--genetics
Protein Binding
Protein Structure, Tertiary
Proto-Oncogene Proteins c-myc--chemistry
RNA, Messenger--genetics
Repressor Proteins--metabolism
Transcription, Genetic