SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization.

Han, Myung-Kwan

SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. [electronic resource] - Cell stem cell Mar 2008 - 241-51 p. digital

Publication Type: Journal Article

1875-9777

10.1016/j.stem.2008.01.002 doi


Active Transport, Cell Nucleus--physiology
Animals
Apoptosis--physiology
Cell Nucleus--genetics
Cells, Cultured
Cytoplasm--genetics
Embryonic Stem Cells--cytology
Homeodomain Proteins--genetics
Mice
Mice, Knockout
Mitochondria--genetics
Nanog Homeobox Protein
Reactive Oxygen Species--metabolism
Sirtuin 1
Sirtuins--genetics
Transcriptional Activation--physiology
Tumor Suppressor Protein p53--genetics
bcl-2-Associated X Protein--genetics