Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin.
Wojtkowiak, Jonathan W
Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jul 2008 - 1-11 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1521-0103
10.1124/jpet.107.135830 doi
Animals
Animals, Newborn
Apoptosis--drug effects
Cell Line
Cell Line, Transformed
Cell Line, Tumor
Drug Therapy, Combination
Enzyme Inhibitors--administration & dosage
Farnesyltranstransferase--antagonists & inhibitors
Lovastatin--administration & dosage
Nerve Sheath Neoplasms--drug therapy
Neurofibromatosis 1--drug therapy
Rats
Rats, Sprague-Dawley
Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jul 2008 - 1-11 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1521-0103
10.1124/jpet.107.135830 doi
Animals
Animals, Newborn
Apoptosis--drug effects
Cell Line
Cell Line, Transformed
Cell Line, Tumor
Drug Therapy, Combination
Enzyme Inhibitors--administration & dosage
Farnesyltranstransferase--antagonists & inhibitors
Lovastatin--administration & dosage
Nerve Sheath Neoplasms--drug therapy
Neurofibromatosis 1--drug therapy
Rats
Rats, Sprague-Dawley