Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain.

Nezis, Ioannis P

Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain. [electronic resource] - The Journal of cell biology Mar 2008 - 1065-71 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1540-8140

10.1083/jcb.200711108 doi


Adaptor Proteins, Signal Transducing--chemistry
Aging--metabolism
Animals
Autophagy--genetics
Brain--cytology
DNA-Binding Proteins
Drosophila Proteins--chemistry
Drosophila melanogaster--cytology
Humans
Inclusion Bodies--genetics
Mutation--genetics
Nerve Tissue Proteins--metabolism
Neurodegenerative Diseases--genetics
Nuclear Proteins--chemistry
Proteasome Endopeptidase Complex--genetics
Protein Structure, Tertiary--genetics
Sequestosome-1 Protein
Ubiquitin--genetics
Ubiquitination--genetics