Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages.

Luyendyk, James P

Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Mar 2008 - 4218-26 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0022-1767

10.4049/jimmunol.180.6.4218 doi


Animals
Ascitic Fluid--cytology
Cells, Cultured
Cytokines--antagonists & inhibitors
Down-Regulation--immunology
Female
Gene Expression Regulation, Enzymologic--immunology
Lipopolysaccharides--pharmacology
MAP Kinase Signaling System--immunology
Macrophages, Peritoneal--enzymology
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Monocytes--enzymology
PTEN Phosphohydrolase--biosynthesis
Phosphatidylinositol 3-Kinases--biosynthesis
Proto-Oncogene Proteins c-akt--biosynthesis
Thromboplastin--antagonists & inhibitors
Up-Regulation--immunology