Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension.

Nasim, M Talat

Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension. [electronic resource] - Human molecular genetics Jun 2008 - 1683-94 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1460-2083

10.1093/hmg/ddn059 doi


Aminoglycosides--pharmacology
Bone Morphogenetic Protein Receptors, Type I--metabolism
Bone Morphogenetic Protein Receptors, Type II--genetics
Codon, Nonsense
Exons
Genes, Reporter
Humans
Hypertension, Pulmonary--enzymology
Introns
Phosphorylation
Protein Biosynthesis--genetics
RNA Precursors--metabolism
RNA Splicing--genetics
RNA Stability
RNA, Messenger--metabolism
Signal Transduction
Transcription, Genetic--drug effects