The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands.

Parker, Matthew A

The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands. [electronic resource] - Bioorganic & medicinal chemistry Apr 2008 - 4661-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1464-3391

10.1016/j.bmc.2008.02.033 doi


Anthracenes--chemical synthesis
Catalysis
Hydrophobic and Hydrophilic Interactions
Ligands
Lipids--chemistry
Molecular Structure
Phenethylamines--chemical synthesis
Protein Binding
Receptor, Serotonin, 5-HT2A--metabolism
Serotonin Antagonists--chemical synthesis
Serotonin Receptor Agonists--chemical synthesis