TGF-beta1-induced cardiac myofibroblasts are nonproliferating functional cells carrying DNA damages.

Petrov, Victor V

TGF-beta1-induced cardiac myofibroblasts are nonproliferating functional cells carrying DNA damages. [electronic resource] - Experimental cell research Apr 2008 - 1480-94 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0014-4827

10.1016/j.yexcr.2008.01.014 doi


Animals
Cell Proliferation--drug effects
Collagen--metabolism
Cyclin-Dependent Kinase Inhibitor p15--metabolism
Cyclin-Dependent Kinase Inhibitor p16--metabolism
DNA Damage
DNA Fragmentation--drug effects
Electrophoresis, Agar Gel
Fibroblasts--cytology
G1 Phase--drug effects
In Situ Nick-End Labeling
Ki-67 Antigen--metabolism
Male
Myocardium--cytology
Proliferating Cell Nuclear Antigen--metabolism
Protein-Lysine 6-Oxidase--metabolism
Rats
Rats, Wistar
Smad1 Protein--metabolism
Telomerase--metabolism
Transforming Growth Factor beta1--pharmacology
beta-Galactosidase--metabolism