Homozygous deletions may be markers of nearby heterozygous mutations: The complex deletion at FRA16D in the HCT116 colon cancer cell line removes exons of WWOX.

Alsop, Amber E

Homozygous deletions may be markers of nearby heterozygous mutations: The complex deletion at FRA16D in the HCT116 colon cancer cell line removes exons of WWOX. [electronic resource] - Genes, chromosomes & cancer May 2008 - 437-47 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1098-2264

10.1002/gcc.20548 doi


Base Sequence
Cell Line, Tumor
Chromosomes, Human, Pair 16
Colonic Neoplasms--genetics
DNA Primers
Exons
Gene Deletion
Homozygote
Humans
Mutation
Oxidoreductases--genetics
Polymerase Chain Reaction
RNA, Messenger--genetics
Translocation, Genetic
Tumor Suppressor Proteins--genetics
WW Domain-Containing Oxidoreductase