Inhibition of 11betaHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAy mice.

Sundbom, Maj

Inhibition of 11betaHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAy mice. [electronic resource] - BMC pharmacology Feb 2008 - 3 p. digital

Publication Type: Journal Article

1471-2210

10.1186/1471-2210-8-3 doi


11-beta-Hydroxysteroid Dehydrogenase Type 1--antagonists & inhibitors
Adiponectin--blood
Animals
Blood Glucose--metabolism
Diabetes Mellitus, Experimental--blood
Enzyme Inhibitors--pharmacology
Homeostasis--drug effects
Insulin Resistance
Male
Mice
Mice, Mutant Strains
Phenethylamines--pharmacology
Thiazoles--pharmacology