Intestinal epithelial barrier dysfunction and dendritic cell redistribution during early stages of inflammation in the rat: role for TLR-2 and -4 blockage.

Silva, Manuel A

Intestinal epithelial barrier dysfunction and dendritic cell redistribution during early stages of inflammation in the rat: role for TLR-2 and -4 blockage. [electronic resource] - Inflammatory bowel diseases May 2008 - 632-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1078-0998

10.1002/ibd.20379 doi


Animals
Anti-Inflammatory Agents, Non-Steroidal--toxicity
Antigens, CD--metabolism
Blotting, Western
Dendritic Cells--metabolism
Disease Models, Animal
Disease Progression
Enterocytes--ultrastructure
Epithelial Cells--metabolism
Horseradish Peroxidase--pharmacokinetics
Ileitis--chemically induced
Ileum--drug effects
Immunohistochemistry
Indomethacin--toxicity
Integrin alpha Chains--metabolism
Intestinal Mucosa--metabolism
Male
Microscopy, Electron
Permeability--drug effects
Rats
Rats, Sprague-Dawley
Toll-Like Receptor 2--antagonists & inhibitors
Toll-Like Receptor 4--antagonists & inhibitors