Targeting the calpain/calpastatin system as a new strategy to prevent cardiovascular remodeling in angiotensin II-induced hypertension.
Letavernier, Emmanuel
Targeting the calpain/calpastatin system as a new strategy to prevent cardiovascular remodeling in angiotensin II-induced hypertension. [electronic resource] - Circulation research Mar 2008 - 720-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1524-4571
10.1161/CIRCRESAHA.107.160077 doi
Angiotensin II--administration & dosage
Animals
Aorta--enzymology
Blood Pressure
Calcium-Binding Proteins--genetics
Calpain--antagonists & inhibitors
Cysteine Proteinase Inhibitors--genetics
Disease Models, Animal
Fibrosis
Genetic Therapy--methods
Hypertension--chemically induced
Hypertrophy
Hypertrophy, Left Ventricular--etiology
Inflammation--etiology
Infusion Pumps, Implantable
Mice
Mice, Transgenic
Muscle, Smooth, Vascular--metabolism
Myocardium--enzymology
NF-kappa B--metabolism
NFATC Transcription Factors--metabolism
Renal Artery--enzymology
Time Factors
Ventricular Remodeling
Targeting the calpain/calpastatin system as a new strategy to prevent cardiovascular remodeling in angiotensin II-induced hypertension. [electronic resource] - Circulation research Mar 2008 - 720-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1524-4571
10.1161/CIRCRESAHA.107.160077 doi
Angiotensin II--administration & dosage
Animals
Aorta--enzymology
Blood Pressure
Calcium-Binding Proteins--genetics
Calpain--antagonists & inhibitors
Cysteine Proteinase Inhibitors--genetics
Disease Models, Animal
Fibrosis
Genetic Therapy--methods
Hypertension--chemically induced
Hypertrophy
Hypertrophy, Left Ventricular--etiology
Inflammation--etiology
Infusion Pumps, Implantable
Mice
Mice, Transgenic
Muscle, Smooth, Vascular--metabolism
Myocardium--enzymology
NF-kappa B--metabolism
NFATC Transcription Factors--metabolism
Renal Artery--enzymology
Time Factors
Ventricular Remodeling