Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide.

Kerbey, A L

Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide. [electronic resource] - The Biochemical journal Feb 1976 - 327-48 p. digital

Publication Type: Journal Article

0264-6021

10.1042/bj1540327 doi


Acetates--pharmacology
Acetyl Coenzyme A--metabolism
Adenosine Triphosphate--metabolism
Animals
Caprylates--pharmacology
Carnitine--analogs & derivatives
Cell Membrane--metabolism
Coenzyme A--metabolism
Diabetes Mellitus, Experimental--metabolism
Fatty Acids--metabolism
Heart--drug effects
In Vitro Techniques
Ketoglutaric Acids--pharmacology
Ketone Bodies--metabolism
Malates--metabolism
Male
Mitochondria, Muscle--enzymology
Myocardium--enzymology
NAD--metabolism
Oligomycins--metabolism
Palmitates--pharmacology
Perfusion
Phosphates--metabolism
Pyruvate Dehydrogenase Complex--metabolism
Pyruvates--metabolism
Rats
Succinates--metabolism