Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells.

Wu, Jianqiang

Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. [electronic resource] - Cancer cell Feb 2008 - 105-16 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1535-6108

10.1016/j.ccr.2007.12.027 doi


Animals
Axons--metabolism
Cell Proliferation
Embryo Loss
Embryo, Mammalian--cytology
Ganglia, Spinal--cytology
Hedgehog Proteins--metabolism
Integrases--metabolism
Mice
Models, Biological
Neurofibroma, Plexiform--pathology
Neurofibromin 1--metabolism
Neuroglia--cytology
Peripheral Nerves--metabolism
Peripheral Nervous System Neoplasms--pathology
Pigmentation
Receptor, Nerve Growth Factor--metabolism
Recombination, Genetic
Schwann Cells--pathology
Sciatic Nerve--metabolism
Stem Cells--cytology