PDE4 and PDE5 regulate cyclic nucleotides relaxing effects in human umbilical arteries.

Santos-Silva, António José

PDE4 and PDE5 regulate cyclic nucleotides relaxing effects in human umbilical arteries. [electronic resource] - European journal of pharmacology Mar 2008 - 102-9 p. digital

Publication Type: Journal Article

0014-2999

10.1016/j.ejphar.2007.12.017 doi


1-Methyl-3-isobutylxanthine--pharmacology
Adenylyl Cyclases--metabolism
Colforsin--pharmacology
Cyclic AMP--physiology
Cyclic GMP--physiology
Cyclic Nucleotide Phosphodiesterases, Type 4--biosynthesis
Cyclic Nucleotide Phosphodiesterases, Type 5--biosynthesis
Dipyridamole--pharmacology
Female
Guanylate Cyclase--metabolism
Histamine--pharmacology
Humans
In Vitro Techniques
Isoenzymes--antagonists & inhibitors
Muscle Contraction
Muscle Relaxation
Muscle, Smooth, Vascular--drug effects
Naphthyridines--pharmacology
Nitroprusside--pharmacology
Phosphodiesterase 4 Inhibitors
Phosphodiesterase 5 Inhibitors
Pyrimidines--pharmacology
Reverse Transcriptase Polymerase Chain Reaction
Rolipram--pharmacology
Serotonin--pharmacology
Umbilical Arteries--drug effects
Vasodilator Agents--pharmacology