Mitochondrial dysfunction, oxidative stress, and apoptosis revealed by proteomic and transcriptomic analyses of the striata in two mouse models of Parkinson's disease.

Chin, Mark H

Mitochondrial dysfunction, oxidative stress, and apoptosis revealed by proteomic and transcriptomic analyses of the striata in two mouse models of Parkinson's disease. [electronic resource] - Journal of proteome research Feb 2008 - 666-77 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1535-3893

10.1021/pr070546l doi


Animals
Apoptosis--genetics
Disease Models, Animal
Dopamine--deficiency
Gene Expression Profiling
Male
Mice
Mice, Inbred C57BL
Mitochondria--genetics
Neostriatum--drug effects
Neurotoxins--pharmacology
Oxidative Stress--genetics
Parkinson Disease--genetics
Proteome--genetics
Proteomics
RNA--metabolism