Inhibition of matrix metalloproteinases prevents peroxynitrite-induced contractile dysfunction in the isolated cardiac myocyte.

León, H

Inhibition of matrix metalloproteinases prevents peroxynitrite-induced contractile dysfunction in the isolated cardiac myocyte. [electronic resource] - British journal of pharmacology Feb 2008 - 676-83 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0007-1188

10.1038/sj.bjp.0707621 doi


Animals
Calcium--metabolism
Cardiac Pacing, Artificial
Doxycycline--pharmacology
Enzyme Activation
Homeostasis
Hydroxamic Acids--pharmacology
Male
Matrix Metalloproteinase 2--metabolism
Matrix Metalloproteinase Inhibitors
Myocardial Contraction--drug effects
Myocytes, Cardiac--drug effects
Oligopeptides--pharmacology
Peroxynitrous Acid--metabolism
Protease Inhibitors--pharmacology
Rats
Rats, Sprague-Dawley
Time Factors