Hypoxia increases Abeta generation by altering beta- and gamma-cleavage of APP.

Li, Liang

Hypoxia increases Abeta generation by altering beta- and gamma-cleavage of APP. [electronic resource] - Neurobiology of aging Jul 2009 - 1091-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1558-1497

10.1016/j.neurobiolaging.2007.10.011 doi


Adenine--analogs & derivatives
Alzheimer Disease--genetics
Amyloid beta-Peptides--cerebrospinal fluid
Amyloid beta-Protein Precursor--genetics
Animals
Autophagy--genetics
Brain--metabolism
Cell Line, Tumor
Disease Models, Animal
Endopeptidases
Humans
Hypoxia, Brain--complications
Membrane Proteins--metabolism
Mice
Mice, Transgenic
Peptide Hydrolases--metabolism
Plaque, Amyloid--genetics
Presenilin-1--genetics