Rational design and generation of a bimodal bifunctional ligand for antibody-targeted radiation cancer therapy.

Chong, Hyun-Soon

Rational design and generation of a bimodal bifunctional ligand for antibody-targeted radiation cancer therapy. [electronic resource] - Journal of medicinal chemistry Jan 2008 - 118-25 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

0022-2623

10.1021/jm070401q doi


Animals
Antibodies
Bismuth
Chelating Agents--chemical synthesis
Drug Design
Drug Stability
Female
Glycine--analogs & derivatives
Heterocyclic Compounds, 1-Ring--chemical synthesis
Humans
Isotope Labeling
Kinetics
Ligands
Lutetium
Mice
Mice, Nude
Radioimmunotherapy
Radioisotopes
Radiopharmaceuticals--chemical synthesis
Serum
Spectrophotometry, Ultraviolet
Tissue Distribution