The activation of MEK-ERK1/2 by glutamate receptor-stimulation is involved in the regulation of RPE proliferation and morphologic transformation.
Pacheco-Domínguez, Reyna Lizette
The activation of MEK-ERK1/2 by glutamate receptor-stimulation is involved in the regulation of RPE proliferation and morphologic transformation. [electronic resource] - Experimental eye research Feb 2008 - 207-19 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0014-4835
10.1016/j.exer.2007.10.011 doi
Actins--metabolism
Animals
Cell Proliferation--drug effects
Cells, Cultured
Cytoskeleton--drug effects
Disease Models, Animal
Dose-Response Relationship, Drug
Enzyme Activation--physiology
Glutamic Acid--pharmacology
MAP Kinase Signaling System--drug effects
Microscopy, Confocal
Mitogen-Activated Protein Kinase 1--metabolism
Mitogen-Activated Protein Kinase 3--metabolism
Pigment Epithelium of Eye--cytology
Rats
Rats, Long-Evans
Receptors, Glutamate--physiology
Vitreoretinopathy, Proliferative--enzymology
The activation of MEK-ERK1/2 by glutamate receptor-stimulation is involved in the regulation of RPE proliferation and morphologic transformation. [electronic resource] - Experimental eye research Feb 2008 - 207-19 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0014-4835
10.1016/j.exer.2007.10.011 doi
Actins--metabolism
Animals
Cell Proliferation--drug effects
Cells, Cultured
Cytoskeleton--drug effects
Disease Models, Animal
Dose-Response Relationship, Drug
Enzyme Activation--physiology
Glutamic Acid--pharmacology
MAP Kinase Signaling System--drug effects
Microscopy, Confocal
Mitogen-Activated Protein Kinase 1--metabolism
Mitogen-Activated Protein Kinase 3--metabolism
Pigment Epithelium of Eye--cytology
Rats
Rats, Long-Evans
Receptors, Glutamate--physiology
Vitreoretinopathy, Proliferative--enzymology