Pancreatic cancer cell genetics and signaling response to treatment correlate with efficacy of gemcitabine-based molecular targeting strategies.
Holcomb, Bryan
Pancreatic cancer cell genetics and signaling response to treatment correlate with efficacy of gemcitabine-based molecular targeting strategies. [electronic resource] - Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract Feb 2008 - 288-96 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1091-255X
10.1007/s11605-007-0406-6 doi
Adenocarcinoma--drug therapy
Antimetabolites, Antineoplastic--administration & dosage
Antineoplastic Agents--administration & dosage
Blotting, Western
Cell Proliferation--drug effects
Chromones--administration & dosage
Curcumin--administration & dosage
Deoxycytidine--administration & dosage
Dose-Response Relationship, Drug
Drug Synergism
Drug Therapy, Combination
Electrophoretic Mobility Shift Assay
Enzyme Inhibitors--administration & dosage
Humans
MAP Kinase Signaling System--drug effects
Morpholines--administration & dosage
NF-kappa B--drug effects
Pancreatic Neoplasms--drug therapy
Proto-Oncogene Proteins c-akt--drug effects
Tumor Cells, Cultured
Gemcitabine
Pancreatic cancer cell genetics and signaling response to treatment correlate with efficacy of gemcitabine-based molecular targeting strategies. [electronic resource] - Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract Feb 2008 - 288-96 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1091-255X
10.1007/s11605-007-0406-6 doi
Adenocarcinoma--drug therapy
Antimetabolites, Antineoplastic--administration & dosage
Antineoplastic Agents--administration & dosage
Blotting, Western
Cell Proliferation--drug effects
Chromones--administration & dosage
Curcumin--administration & dosage
Deoxycytidine--administration & dosage
Dose-Response Relationship, Drug
Drug Synergism
Drug Therapy, Combination
Electrophoretic Mobility Shift Assay
Enzyme Inhibitors--administration & dosage
Humans
MAP Kinase Signaling System--drug effects
Morpholines--administration & dosage
NF-kappa B--drug effects
Pancreatic Neoplasms--drug therapy
Proto-Oncogene Proteins c-akt--drug effects
Tumor Cells, Cultured
Gemcitabine