Long-term imatinib therapy promotes bone formation in CML patients.

Fitter, Stephen

Long-term imatinib therapy promotes bone formation in CML patients. [electronic resource] - Blood Mar 2008 - 2538-47 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-4971

10.1182/blood-2007-07-104281 doi


Adipogenesis--drug effects
Adult
Aged
Antineoplastic Agents--pharmacology
Benzamides
Calcification, Physiologic--drug effects
Calcium--blood
Cell Proliferation--drug effects
Enzyme Activation--drug effects
Female
Gene Expression Regulation, Leukemic--drug effects
Humans
Imatinib Mesylate
Leukemia, Myelogenous, Chronic, BCR-ABL Positive--drug therapy
Male
Mesenchymal Stem Cells--drug effects
Middle Aged
Organ Size--drug effects
Osteogenesis--drug effects
Phosphates--blood
Piperazines--pharmacology
Platelet-Derived Growth Factor--pharmacology
Proto-Oncogene Proteins c-akt--metabolism
Proto-Oncogene Proteins c-crk--metabolism
Pyrimidines--pharmacology
Time Factors