Simvastatin suppresses lung inflammatory response in a rat cardiopulmonary bypass model.

Shao, Hongtao

Simvastatin suppresses lung inflammatory response in a rat cardiopulmonary bypass model. [electronic resource] - The Annals of thoracic surgery Dec 2007 - 2011-8 p. digital

Publication Type: Journal Article

1552-6259

10.1016/j.athoracsur.2007.07.022 doi


Animals
Cardiopulmonary Bypass--adverse effects
Chemokine CCL2--analysis
Dose-Response Relationship, Drug
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Immunity, Innate--drug effects
Inflammation--prevention & control
Interleukin-6--analysis
Lung--drug effects
Male
NF-kappa B--metabolism
Rats
Rats, Sprague-Dawley
Simvastatin--pharmacology
Toll-Like Receptor 4--genetics
Tumor Necrosis Factor-alpha--analysis