Design and synthesis of indole-based peptoids as potent noncompetitive antagonists of transient receptor potential vanilloid 1.

Quintanar-Audelo, Martina

Design and synthesis of indole-based peptoids as potent noncompetitive antagonists of transient receptor potential vanilloid 1. [electronic resource] - Journal of medicinal chemistry Nov 2007 - 6133-43 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm070612v doi


Analgesics--chemical synthesis
Animals
Drug Design
In Vitro Techniques
Indoles--chemical synthesis
Oligopeptides--chemical synthesis
Oocytes--drug effects
Patch-Clamp Techniques
Peptoids--chemical synthesis
Rats
Structure-Activity Relationship
TRPV Cation Channels--antagonists & inhibitors
Xenopus