Dual roles of IL-15 in maintaining IL-7RalphalowCCR7- memory CD8+ T cells in humans via recovering the phosphatidylinositol 3-kinase/AKT pathway.

Kim, Hang-Rae

Dual roles of IL-15 in maintaining IL-7RalphalowCCR7- memory CD8+ T cells in humans via recovering the phosphatidylinositol 3-kinase/AKT pathway. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Nov 2007 - 6734-40 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0022-1767

10.4049/jimmunol.179.10.6734 doi


CD8-Positive T-Lymphocytes--enzymology
Cell Proliferation
Cell Survival--physiology
Enzyme Activation--immunology
Gene Expression Regulation--immunology
Humans
Immunologic Memory--physiology
Infections--enzymology
Interleukin-15--immunology
Interleukin-2 Receptor beta Subunit
Interleukin-7--immunology
Neoplasms--enzymology
Perforin--immunology
Phosphatidylinositol 3-Kinases--immunology
Proto-Oncogene Proteins c-akt--immunology
Receptors, Antigen, T-Cell--immunology
Receptors, CCR7
Receptors, Interleukin-17--biosynthesis
Signal Transduction--immunology