Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth.

Chesnokova, Vera

Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth. [electronic resource] - Cancer research Nov 2007 - 10564-72 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1538-7445

10.1158/0008-5472.CAN-07-0974 doi


Aging
Aneuploidy
Animals
Cell Cycle
Cyclin-Dependent Kinase Inhibitor p21--physiology
DNA Damage
Female
Male
Mice
Mice, Inbred C57BL
Neoplasm Proteins--physiology
Organ Size
Pituitary Gland--pathology
Pituitary Neoplasms--prevention & control
Promoter Regions, Genetic
Retinoblastoma Protein--physiology
Securin
Signal Transduction
Sp1 Transcription Factor--physiology
Telomere
Tumor Suppressor Protein p53--physiology