Production of P-glycoprotein from the MDR1 upstream promoter is insufficient to affect the response to first-line chemotherapy in advanced breast cancer.

Raguz, Selina

Production of P-glycoprotein from the MDR1 upstream promoter is insufficient to affect the response to first-line chemotherapy in advanced breast cancer. [electronic resource] - International journal of cancer Mar 2008 - 1058-67 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-0215

10.1002/ijc.23149 doi


ATP Binding Cassette Transporter, Subfamily B, Member 1--genetics
Adult
Antineoplastic Agents--therapeutic use
Breast Neoplasms--drug therapy
Cloning, Molecular
Drug Resistance, Multiple--genetics
Electrophoretic Mobility Shift Assay
Female
Genes, MDR
Humans
Middle Aged
Promoter Regions, Genetic--genetics
RNA, Messenger--analysis
Reverse Transcriptase Polymerase Chain Reaction