COX-2 inhibitor nimesulide protects rat heart against oxidative stress by improving endothelial function and enhancing NO production.

Lv, Ping-Ping

COX-2 inhibitor nimesulide protects rat heart against oxidative stress by improving endothelial function and enhancing NO production. [electronic resource] - Sheng li xue bao : [Acta physiologica Sinica] Oct 2007 - 674-80 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0371-0874


Animals
Coronary Vessels
Cyclooxygenase 2 Inhibitors
Endothelium, Vascular
Endothelium-Dependent Relaxing Factors
Heart--drug effects
Hydrogen Peroxide
Myocardial Reperfusion Injury
Myocardium
NG-Nitroarginine Methyl Ester
Nitric Oxide--metabolism
Oxidative Stress
Rats
Rats, Sprague-Dawley
Serotonin
Sulfonamides--pharmacology
Vasodilation
Vasodilator Agents