Indomethacin induces apoptosis via a MRP1-dependent mechanism in doxorubicin-resistant small-cell lung cancer cells overexpressing MRP1.
de Groot, D J A
Indomethacin induces apoptosis via a MRP1-dependent mechanism in doxorubicin-resistant small-cell lung cancer cells overexpressing MRP1. [electronic resource] - British journal of cancer Oct 2007 - 1077-83 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0007-0920
10.1038/sj.bjc.6604010 doi
ATP Binding Cassette Transporter, Subfamily B, Member 1--drug effects
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Antibiotics, Antineoplastic--pharmacology
Apoptosis--drug effects
Carcinoma, Small Cell--drug therapy
Cell Line, Tumor
Doxorubicin--pharmacology
Drug Resistance, Neoplasm--physiology
Flow Cytometry
Glutathione--drug effects
Humans
Indomethacin--pharmacology
Lung Neoplasms--drug therapy
Membrane Potential, Mitochondrial--drug effects
RNA, Messenger--analysis
RNA, Small Interfering
Reverse Transcriptase Polymerase Chain Reaction
Indomethacin induces apoptosis via a MRP1-dependent mechanism in doxorubicin-resistant small-cell lung cancer cells overexpressing MRP1. [electronic resource] - British journal of cancer Oct 2007 - 1077-83 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0007-0920
10.1038/sj.bjc.6604010 doi
ATP Binding Cassette Transporter, Subfamily B, Member 1--drug effects
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Antibiotics, Antineoplastic--pharmacology
Apoptosis--drug effects
Carcinoma, Small Cell--drug therapy
Cell Line, Tumor
Doxorubicin--pharmacology
Drug Resistance, Neoplasm--physiology
Flow Cytometry
Glutathione--drug effects
Humans
Indomethacin--pharmacology
Lung Neoplasms--drug therapy
Membrane Potential, Mitochondrial--drug effects
RNA, Messenger--analysis
RNA, Small Interfering
Reverse Transcriptase Polymerase Chain Reaction