Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains.

Mai, Antonello

Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains. [electronic resource] - Journal of medicinal chemistry Nov 2007 - 5412-24 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm070811e doi


Anti-HIV Agents--chemical synthesis
Cell Line
Drug Resistance, Viral
HIV Reverse Transcriptase--genetics
HIV-1--drug effects
Humans
Models, Molecular
Mutation
Protein Binding
Pyrimidines--chemical synthesis
Reverse Transcriptase Inhibitors--chemical synthesis
Structure-Activity Relationship