Depletion of the catalytic subunit of protein phosphatase-2A (PP2Ac) markedly attenuates glucose-stimulated insulin secretion in pancreatic beta-cells.

Jangati, Giridhar R

Depletion of the catalytic subunit of protein phosphatase-2A (PP2Ac) markedly attenuates glucose-stimulated insulin secretion in pancreatic beta-cells. [electronic resource] - Endocrine Jun 2007 - 248-53 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1355-008X

10.1007/s12020-007-0046-3 doi


Animals
Clone Cells
Glucose--metabolism
Insulin--biosynthesis
Insulin Secretion
Insulin-Secreting Cells--cytology
Islets of Langerhans--cytology
Male
Protein Phosphatase 2--physiology
RNA Interference
Rats
Rats, Sprague-Dawley
Signal Transduction