An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC)-including relative predictivity of regulatory tests and rodent carcinogenesis and performance with autofluorescent and coloured compounds.
Knight, Andrew W
An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC)-including relative predictivity of regulatory tests and rodent carcinogenesis and performance with autofluorescent and coloured compounds. [electronic resource] - Mutagenesis Nov 2007 - 409-16 p. digital
Publication Type: Journal Article
0267-8357
10.1093/mutage/gem036 doi
Animals
Carcinogens--toxicity
Coloring Agents--toxicity
Comet Assay
DNA Damage
DNA Helicases
DNA Repair Enzymes
Fluorescence
Gene Expression Regulation--drug effects
Green Fluorescent Proteins--biosynthesis
Liver--drug effects
Mutagenicity Tests--standards
Promoter Regions, Genetic
Rats
Reproducibility of Results
Saccharomyces cerevisiae--drug effects
Saccharomyces cerevisiae Proteins--biosynthesis
Sensitivity and Specificity
An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC)-including relative predictivity of regulatory tests and rodent carcinogenesis and performance with autofluorescent and coloured compounds. [electronic resource] - Mutagenesis Nov 2007 - 409-16 p. digital
Publication Type: Journal Article
0267-8357
10.1093/mutage/gem036 doi
Animals
Carcinogens--toxicity
Coloring Agents--toxicity
Comet Assay
DNA Damage
DNA Helicases
DNA Repair Enzymes
Fluorescence
Gene Expression Regulation--drug effects
Green Fluorescent Proteins--biosynthesis
Liver--drug effects
Mutagenicity Tests--standards
Promoter Regions, Genetic
Rats
Reproducibility of Results
Saccharomyces cerevisiae--drug effects
Saccharomyces cerevisiae Proteins--biosynthesis
Sensitivity and Specificity