Endocytosis of DNA-Hsp65 alters the pH of the late endosome/lysosome and interferes with antigen presentation.

Trombone, Ana Paula F

Endocytosis of DNA-Hsp65 alters the pH of the late endosome/lysosome and interferes with antigen presentation. [electronic resource] - PloS one Sep 2007 - e923 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0000923 doi


Animals
Antigen Presentation--immunology
Bacterial Proteins--genetics
Biological Transport
Cell Line
Chaperonin 60
Chaperonins--genetics
Clathrin--metabolism
DNA, Complementary--genetics
Endocytosis--physiology
Endosomes--metabolism
Hemocyanins--immunology
Hydrogen-Ion Concentration
Lysosomes--metabolism
Macrophages--cytology
Mice
Mice, Knockout
Microscopy, Confocal
Plasmids--genetics
Toll-Like Receptor 9--genetics
Transferrin--metabolism