ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging.

Vishnubhotla, Ramana

ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging. [electronic resource] - Laboratory investigation; a journal of technical methods and pathology Nov 2007 - 1149-58 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1530-0307

10.1038/labinvest.3700674 doi


Actin Cytoskeleton--metabolism
Cell Line
Cell Proliferation
Collagen Type I--metabolism
Colonic Neoplasms--enzymology
Enzyme Activation
Epithelial Cells--enzymology
Humans
Matrix Metalloproteinase 13--metabolism
Matrix Metalloproteinase 2--metabolism
Matrix Metalloproteinase 9--metabolism
Microscopy, Fluorescence, Multiphoton
Neoplasm Invasiveness
Pseudopodia--metabolism
rho-Associated Kinases--metabolism