Population pharmacokinetics of tacrolimus and CYP3A5, MDR1 and IL-10 polymorphisms in adult liver transplant patients.

Li, D

Population pharmacokinetics of tacrolimus and CYP3A5, MDR1 and IL-10 polymorphisms in adult liver transplant patients. [electronic resource] - Journal of clinical pharmacy and therapeutics Oct 2007 - 505-15 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0269-4727

10.1111/j.1365-2710.2007.00850.x doi


ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1--genetics
Adult
Aged
Alleles
Area Under Curve
Asian People
Bilirubin--blood
China
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--genetics
Female
Genotype
Humans
Immunosuppressive Agents--administration & dosage
Interleukin-10--genetics
Liver--metabolism
Liver Transplantation
Male
Metabolic Clearance Rate
Middle Aged
Models, Biological
Polymorphism, Genetic
Tacrolimus--administration & dosage