A common mechanism of cellular death induced by bactericidal antibiotics.

Kohanski, Michael A

A common mechanism of cellular death induced by bactericidal antibiotics. [electronic resource] - Cell Sep 2007 - 797-810 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

0092-8674

10.1016/j.cell.2007.06.049 doi


2,2'-Dipyridyl--pharmacology
Ampicillin--pharmacology
Anti-Bacterial Agents--classification
Carbon-Sulfur Lyases--genetics
Cell Death--drug effects
Citric Acid Cycle--drug effects
Colony Count, Microbial
DNA Damage
DNA, Bacterial--drug effects
Escherichia coli--drug effects
Escherichia coli Proteins--genetics
Ferrous Compounds--metabolism
Free Radical Scavengers--pharmacology
Gene Expression Profiling
Gene Expression Regulation, Bacterial--drug effects
Hydrogen Peroxide--metabolism
Hydroxyl Radical--metabolism
Hydroxyurea--pharmacology
Iron Chelating Agents--pharmacology
Kanamycin--pharmacology
Membrane Proteins--genetics
Microbial Viability--drug effects
Mutation
NAD--metabolism
Norfloxacin--pharmacology
Oxidative Stress--drug effects
Rec A Recombinases--genetics
Staphylococcus aureus--drug effects
Time Factors