The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib.
Hantschel, Oliver
The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Aug 2007 - 13283-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0027-8424
10.1073/pnas.0702654104 doi
Animals
Basophils--drug effects
Dasatinib
Enzyme-Linked Immunosorbent Assay
Fusion Proteins, bcr-abl
Histamine Release--drug effects
Humans
K562 Cells
Mice
Mice, Inbred C57BL
Protein Kinase Inhibitors--pharmacology
Protein-Tyrosine Kinases--antagonists & inhibitors
Pyrimidines--pharmacology
Thiazoles--pharmacology
U937 Cells
The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Aug 2007 - 13283-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0027-8424
10.1073/pnas.0702654104 doi
Animals
Basophils--drug effects
Dasatinib
Enzyme-Linked Immunosorbent Assay
Fusion Proteins, bcr-abl
Histamine Release--drug effects
Humans
K562 Cells
Mice
Mice, Inbred C57BL
Protein Kinase Inhibitors--pharmacology
Protein-Tyrosine Kinases--antagonists & inhibitors
Pyrimidines--pharmacology
Thiazoles--pharmacology
U937 Cells