PD-1-PD-L1 pathway is involved in suppressing alloreactivity of heart infiltrating t cells during murine gvhd across minor histocompatibility antigen barriers.

Schilbach, Karin

PD-1-PD-L1 pathway is involved in suppressing alloreactivity of heart infiltrating t cells during murine gvhd across minor histocompatibility antigen barriers. [electronic resource] - Transplantation Jul 2007 - 214-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0041-1337

10.1097/01.tp.0000268074.77929.54 doi


Animals
Antigens, CD--biosynthesis
Antigens, Differentiation--biosynthesis
Antigens, Surface--biosynthesis
Apoptosis Regulatory Proteins--biosynthesis
B7-1 Antigen--biosynthesis
B7-H1 Antigen
Basic Helix-Loop-Helix Transcription Factors--biosynthesis
CD4-Positive T-Lymphocytes--immunology
CTLA-4 Antigen
Dendritic Cells--immunology
Disease Models, Animal
Female
Gene Expression
Graft vs Host Disease--complications
Heart Diseases--etiology
Hematopoietic Stem Cell Transplantation--adverse effects
Ileum--metabolism
Lymphocyte Activation
Membrane Glycoproteins--biosynthesis
Mice
Mice, Inbred BALB C
Minor Histocompatibility Antigens--immunology
Myocardium--metabolism
Peptides--genetics
Polymerase Chain Reaction
Programmed Cell Death 1 Receptor
RNA, Messenger--genetics
Transplantation, Autologous