Calcitonin gene-related peptide-evoked sustained tachycardia in calcitonin receptor-like receptor transgenic mice is mediated by sympathetic activity.

Kunz, Thomas H

Calcitonin gene-related peptide-evoked sustained tachycardia in calcitonin receptor-like receptor transgenic mice is mediated by sympathetic activity. [electronic resource] - American journal of physiology. Heart and circulatory physiology Oct 2007 - H2155-60 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0363-6135

10.1152/ajpheart.00629.2007 doi


Adrenergic beta-Antagonists--pharmacology
Adrenomedullin--metabolism
Animals
Blood Pressure
Calcitonin Gene-Related Peptide--metabolism
Calcitonin Receptor-Like Protein
Dimerization
Heart--drug effects
Heart Rate
Hexamethonium--pharmacology
Hypotension--metabolism
Intracellular Signaling Peptides and Proteins--metabolism
Membrane Proteins--metabolism
Mice
Mice, Transgenic
Myocardial Contraction
Myocardium--metabolism
Nicotinic Antagonists--pharmacology
Peptide Fragments--pharmacology
Propranolol--pharmacology
Rats
Receptor Activity-Modifying Protein 2
Receptor Activity-Modifying Proteins
Receptors, Calcitonin--antagonists & inhibitors
Recombinant Fusion Proteins--metabolism
Superior Cervical Ganglion--metabolism
Sympathetic Fibers, Postganglionic--metabolism
Sympathetic Nervous System--drug effects
Tachycardia--metabolism