Sickle cell disease: role of reactive oxygen and nitrogen metabolites.

Wood, Katherine C

Sickle cell disease: role of reactive oxygen and nitrogen metabolites. [electronic resource] - Clinical and experimental pharmacology & physiology Sep 2007 - 926-32 p. digital

Publication Type: Journal Article; Review

0305-1870

10.1111/j.1440-1681.2007.04639.x doi


Anemia, Sickle Cell--blood
Animals
Antioxidants--therapeutic use
Antisickling Agents--pharmacology
Endothelium, Vascular--drug effects
Enzyme Inhibitors--therapeutic use
Erythrocyte Aggregation
Hemoglobin, Sickle--metabolism
Hemolysis
Humans
Hydroxyurea--therapeutic use
Iron Chelating Agents--therapeutic use
Leukocyte Rolling
NADPH Oxidases--antagonists & inhibitors
Nitric Oxide--metabolism
Nitric Oxide Synthase--metabolism
Oxidative Stress--drug effects
Platelet Adhesiveness
Reactive Nitrogen Species--blood
Reactive Oxygen Species--blood
Vasodilation
Xanthine Oxidase--metabolism