Pyrene-induced CYP1A2 and SULT1A1 may be regulated by CAR and not by AhR.
Lee, Chul-Ho
Pyrene-induced CYP1A2 and SULT1A1 may be regulated by CAR and not by AhR. [electronic resource] - Toxicology Sep 2007 - 147-56 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0300-483X
10.1016/j.tox.2007.05.026 doi
Animals
Arylsulfotransferase--genetics
Blotting, Western
Constitutive Androstane Receptor
Cytochrome P-450 CYP1A1--genetics
Cytochrome P-450 CYP1A2--genetics
Dose-Response Relationship, Drug
Fluorescent Dyes--administration & dosage
Genotype
Glucuronates--metabolism
Glucuronosyltransferase--genetics
Hydroxylation--drug effects
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Naphthols--metabolism
Pyrenes--administration & dosage
RNA, Messenger--genetics
Receptors, Aryl Hydrocarbon--physiology
Receptors, Cytoplasmic and Nuclear--physiology
Substrate Specificity
Transcription Factors--physiology
Pyrene-induced CYP1A2 and SULT1A1 may be regulated by CAR and not by AhR. [electronic resource] - Toxicology Sep 2007 - 147-56 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0300-483X
10.1016/j.tox.2007.05.026 doi
Animals
Arylsulfotransferase--genetics
Blotting, Western
Constitutive Androstane Receptor
Cytochrome P-450 CYP1A1--genetics
Cytochrome P-450 CYP1A2--genetics
Dose-Response Relationship, Drug
Fluorescent Dyes--administration & dosage
Genotype
Glucuronates--metabolism
Glucuronosyltransferase--genetics
Hydroxylation--drug effects
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Naphthols--metabolism
Pyrenes--administration & dosage
RNA, Messenger--genetics
Receptors, Aryl Hydrocarbon--physiology
Receptors, Cytoplasmic and Nuclear--physiology
Substrate Specificity
Transcription Factors--physiology