NK cells rapidly reject allogeneic bone marrow in the spleen through a perforin- and Ly49D-dependent, but NKG2D-independent mechanism.

Hamby, K

NK cells rapidly reject allogeneic bone marrow in the spleen through a perforin- and Ly49D-dependent, but NKG2D-independent mechanism. [electronic resource] - American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Aug 2007 - 1884-96 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1600-6135

10.1111/j.1600-6143.2007.01864.x doi


Animals
Antigens, Ly--immunology
Antigens, Surface
Bone Marrow Cells--immunology
Bone Marrow Transplantation--immunology
Chimerism
Connexins--metabolism
Disease Models, Animal
Eye Proteins--metabolism
Flow Cytometry
Graft Rejection--genetics
Immunity, Cellular
Killer Cells, Natural--immunology
Lectins, C-Type--immunology
Lymph Nodes--immunology
Membrane Glycoproteins--metabolism
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
NK Cell Lectin-Like Receptor Subfamily A
NK Cell Lectin-Like Receptor Subfamily K
Perforin
Pore Forming Cytotoxic Proteins--metabolism
Receptors, Immunologic--metabolism
Receptors, NK Cell Lectin-Like
Receptors, Natural Killer Cell
Spleen--immunology
T-Lymphocytes, Cytotoxic--immunology
Transplantation, Homologous