3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositide 3-kinases independently of autophagy inhibition.

Ito, Shingo

3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositide 3-kinases independently of autophagy inhibition. [electronic resource] - International journal of oncology Aug 2007 - 261-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1019-6439


Actins--metabolism
Adenine--analogs & derivatives
Apoptosis
Apoptosis Regulatory Proteins--biosynthesis
Autophagy
Beclin-1
Cell Line, Tumor
Cell Membrane--metabolism
Cell Movement
Cell Survival
Chromones--pharmacology
GTP Phosphohydrolases--metabolism
Gene Expression Regulation, Neoplastic
Humans
Membrane Proteins--biosynthesis
Morpholines--pharmacology
Phosphatidylinositol 3-Kinases--metabolism
Protein Kinase Inhibitors--pharmacology