Effects of genetic variation in the novel organic cation transporter, OCTN1, on the renal clearance of gabapentin.

Urban, T J

Effects of genetic variation in the novel organic cation transporter, OCTN1, on the renal clearance of gabapentin. [electronic resource] - Clinical pharmacology and therapeutics Mar 2008 - 416-21 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1532-6535

10.1038/sj.clpt.6100271 doi


Adolescent
Adult
Amines--blood
Cell Line
Cohort Studies
Cyclohexanecarboxylic Acids--blood
Female
Gabapentin
Genetic Variation--genetics
Glomerular Filtration Rate--genetics
Humans
Kidney Tubules--metabolism
Leucine--genetics
Male
Metabolic Clearance Rate--genetics
Organic Cation Transporter 1--genetics
Phenylalanine--genetics
Polymorphism, Genetic
Reference Values
gamma-Aminobutyric Acid--blood