Structure-based design of alpha-amido aldehyde containing gluten peptide analogues as modulators of HLA-DQ2 and transglutaminase 2.
Siegel, Matthew
Structure-based design of alpha-amido aldehyde containing gluten peptide analogues as modulators of HLA-DQ2 and transglutaminase 2. [electronic resource] - Bioorganic & medicinal chemistry Sep 2007 - 6253-61 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0968-0896
10.1016/j.bmc.2007.06.020 doi
Aldehydes--chemistry
Amides--chemistry
Antigen Presentation
Binding Sites
Cell Proliferation--drug effects
Drug Design
Enzyme Inhibitors--chemistry
GTP-Binding Proteins--antagonists & inhibitors
Gamma Rays
Glutens--chemistry
HLA-DQ Antigens--chemistry
Humans
Ligands
Models, Molecular
Peptide Fragments--chemistry
Protein Glutamine gamma Glutamyltransferase 2
T-Lymphocytes--drug effects
Transglutaminases--antagonists & inhibitors
Structure-based design of alpha-amido aldehyde containing gluten peptide analogues as modulators of HLA-DQ2 and transglutaminase 2. [electronic resource] - Bioorganic & medicinal chemistry Sep 2007 - 6253-61 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0968-0896
10.1016/j.bmc.2007.06.020 doi
Aldehydes--chemistry
Amides--chemistry
Antigen Presentation
Binding Sites
Cell Proliferation--drug effects
Drug Design
Enzyme Inhibitors--chemistry
GTP-Binding Proteins--antagonists & inhibitors
Gamma Rays
Glutens--chemistry
HLA-DQ Antigens--chemistry
Humans
Ligands
Models, Molecular
Peptide Fragments--chemistry
Protein Glutamine gamma Glutamyltransferase 2
T-Lymphocytes--drug effects
Transglutaminases--antagonists & inhibitors