Mycophenolate mofetil administration reduces renal inflammation, oxidative stress, and arterial pressure in rats with lead-induced hypertension.

Bravo, Yanauri

Mycophenolate mofetil administration reduces renal inflammation, oxidative stress, and arterial pressure in rats with lead-induced hypertension. [electronic resource] - American journal of physiology. Renal physiology Aug 2007 - F616-23 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1931-857X

10.1152/ajprenal.00507.2006 doi


Angiotensin II--metabolism
Animals
Blood Pressure--drug effects
Body Weight--drug effects
Creatinine--blood
Hypertension--chemically induced
Immunosuppressive Agents--pharmacology
Inflammation--chemically induced
Kidney Diseases--chemically induced
Lead--blood
Lymphocytes--pathology
Macrophages--pathology
Male
Malondialdehyde--urine
Mycophenolic Acid--analogs & derivatives
Oxidative Stress--drug effects
Proteinuria--chemically induced
Rats
Rats, Sprague-Dawley
Superoxides--metabolism
Transcription Factor RelA--metabolism