High-throughput cytochrome P450 inhibition assays using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry.

Wu, Jin

High-throughput cytochrome P450 inhibition assays using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry. [electronic resource] - Analytical chemistry Jun 2007 - 4657-65 p. digital

Publication Type: Comparative Study; Journal Article

0003-2700

10.1021/ac070221o doi


Acetaminophen--analysis
Atmospheric Pressure
Binding, Competitive
Biological Assay--methods
Chromatography, Liquid--methods
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--analysis
Dextrorphan--analysis
Diclofenac--analogs & derivatives
Enzyme Inhibitors--pharmacology
Hydroxytestosterones--analysis
Lasers
Protein Isoforms--analysis
Reproducibility of Results
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization--methods
Time Factors